2014-01-01

The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) is a general cancer questionnaire that serves as the core measure of the EORTC’s modular approach to the assessment of health-related quality of …

• In the physical, emotional and role/functional domains, the FACT-G and QLQ-C30 have similar responsiveness, statistical efficiency and hence power and sample size requirements. For each category of change in the SSQ, the corresponding differences were calculated in QLQ-C30 mean scores and effect sizes were determined. RESULTS For patients who indicated "no change" in the SSQ, the mean change in scores in the corresponding QLQ-C30 domains was not significantly different from 0. The QLQ-C30 includes 15 domains (Global Health Status/QOL, Physical Functioning, Role Functioning, Emotional Functioning, Cognitive Functioning, Social Functioning, Fatigue, Nausea and Vomiting, Pain, Dyspnea, Insomnia, Appetite Loss, Constipation, Diarrhea and Financial Difficulties); and the QLQ-MY20 includes four domains (Disease Symptoms, Side-Effects of Treatment, Body Image and Future For QLQ-C30 domains with AUC C 0.70, we calculated the sensitivity, specificity, and predictive value of various cutoffs for identifying unmet needs.

Qlq-c30 domains

This approach can be problem-atic as it uses the same threshold for all QLQ-C30 domains. As has been shown in Item Response The-ory analyses [13], the QLQ-C30 items differ in item The EORTC QLQ-C30 consists of 30 questions, resulting in a two-item global health status/QoL scale, five multi-item functional scales (physical functioning, role functioning, emotional functioning, cognitive functioning and social functioning), three multi-item symptom scales (fatigue, nausea/vomiting and pain) and six single-item symptom The EORTC QLQ-C30 domains of pain and physical and role functioning performed well in that they converged and diverged appropriately with the other instruments. The domain of psychological functioning had strong associations with domains thought to be dissimilar (social interaction and fatigue). For QLQ-C30, higher (better) scores in all functioning (e.g. physical functioning, HR 0.432 [0.351–0.533]) or global domains were significantly associated with longer OS (p < 0.03); whereas higher (worse) scores in fatigue, nausea/vomiting, pain (HR 1.865 [1.584–2.197]), dyspnea, insomnia, appetite loss, diarrhea and financial difficulties Variables for the discriminant analysis were selected to correspond as closely as possible to the content of the QLQ-C30 domains. In some cases, the content was quite similar (e.g., pain on the QLQ-C30 and pain on the SCNS-SF34). For a few QLQ-C30 domains, there was no SCNS-SF34 item or domain with similar content.

being developed for the EORTC QLQ-C30. They can guide health care professionals to correctly identify and interpret changes in QoL scores that are meaningful to patients. Clinicians explicitly state that they need threshold scores to enable them to correctly interpret the results for individual patients.

Ninety‐six patients with head and neck cancer completed the EORTC QLQ‐C30/H&N35 and questions on supportive care needs. For all EORTC domains with the ability to discriminate between patients with and without unmet needs (area under the receiver operating characteristic curve [AUC] ≥0.70), the accuracy (eg, sensitivity and specificity) of potential cutoff scores were calculated. Responses to the 40 PRO items were described and psychometric analyses based on Rasch measurement theory (RMT) were conducted on the original multi-item domains of the EORTC QLQ-C30.

In the social domain, the QLQ-C30 scale was more responsive [DR = 0.28 (0.024, 0.54)] and more efficient within arm only [RE = 5.25 (1.21, 232.26)]. In the physical, functional/role, and emotional domains, neither questionnaire was more responsive or efficient.

The test–retest reliability coefficients for most domains are >0.80 except for appetite loss (0.77) and diarrhea (0.75). The QOL score changes after treatments were key domains of the EORTC QLQ-C30: physical functioning, emotional functioning , fatigue and pain. Johannes M. Giesinger1, Wilma Kuijpers1, Teresa Young2, The QLQ-C30 is a more general instrument that is also important but tests domains that may not be directly relevant in patients with bone metastases and short 25 Jan 2011 The EORTC QLQ-C30 and the Medical Outcomes Study Short Form 36 (SF-36) have five domains in common: physical function, mental descriptive analysis of EORTC QLQ-C30 data, consisting of profile plots per visit namic concept incorporating at least three domains: physical, psychological, 13 Dec 2019 Conclusions Selected scales from the EORTC QLQ-C30 can be used to and found that the generic domains of the UW-QOL (including pain, Defined as ITT population who completed the QLQ-C30 assessment at baseline BEFORE THE END OF THE CONSOLIDATION PHASEa FOR ALL DOMAINS.

physical functioning, HR 0.432 [0.351–0.533]) or global domains were significantly associated with longer OS (p < 0.03); whereas higher (worse) scores in fatigue, nausea/vomiting, pain (HR 1.865 [1.584–2.197]), dyspnea, insomnia, appetite loss, diarrhea and financial difficulties were significantly associated with shorter OS (p < 0.01). 2018-09-14 · The Cronbach’s alpha coefficients (internal consistency) are close or greater than 0.7 in all domains of the functional scales of the EORTC QLQ-C30. However, for symptom scales of the EORTC QLQ-C30 questionnaire, alpha coefficients were less than 0.7. 2019-06-27 · Fig 2 illustrates the time-dependent changes in the mean scores for each QLQ-C30 domain from baseline. Primary QOL analyses were performed for three assessments obtained from baseline up to Week 7 to compare these changes between the intervention group (i.e., Group A) and the control group (i.e., Group B) in the initial phase.
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It contains five functional scales (measuring physical, role The derivation of the QLU-C10D health state classification system is described elsewhere. 8 In brief, adapting previously used methods, 11 the MAUCa Consortium identified core QLQ-C30 domains, confirmatory factor analysis confirmed the QLQ-C30 measurement model, and results from Rasch and psychometric analyses, as well as patient preferences, guided item selection. 2019-01-29 2016-06-07 · Thresholds for clinical importance for four key domains of the EORTC QLQ-C30: physical functioning, emotional functioning, fatigue and pain Abstract. The EORTC QLQ-C30 is one of the most widely used quality of life questionnaires in cancer research.

The standard FACT-G scoring algorithm is simply to sum responses of component items, after reversing selected items such that higher score represents better HRQOL for all [6] . Se hela listan på mja.com.au 2013-03-27 · Variables for the discriminant analysis were selected to correspond as closely as possible to the content of the QLQ-C30 domains. In some cases, the content was quite similar (e.g., pain on the QLQ-C30 and pain on the SCNS-SF34).
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dresses physical attractiveness. As with the QLQ-C30, QLQ-MY20 domain scores are averaged and transformed linearlytoascorerangingfrom0–100. A high score for Disease Symptoms and Side Effects of Treatment repre-sents a high level of symptomatology or problems, whereas a high score for Future Perspective and Body Image represents better outcomes.

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2013-03-27 · Variables for the discriminant analysis were selected to correspond as closely as possible to the content of the QLQ-C30 domains. In some cases, the content was quite similar (e.g., pain on the QLQ-C30 and pain on the SCNS-SF34). For a few QLQ-C30 domains, there was no SCNS-SF34 item or domain with similar content.

The new instrument comprises a total of 262 items. Developed software for conducting online CAT assessment and for selecting items for short forms For the EU sample, most QLQ-C30 domains showed differences by sex/age, with men scoring somewhat better health than women, while age effects varied across domains. The QLQ-C30 has a global HRQOL scale (component items shown in Table 1), whereas the total score of the FACT-G is used as a composite measure of HRQOL.

For each QLQ-C30 domain a so-called item bank, from which the CAT selects the items for each patient, has been developed. The new items have the same item and response format as the QLQ-C30 items. The new instrument encompasses a total of 262 items.

Results: FACT-G total score was more efficient 5 Sep 2018 The EORTC QLQ-MY20 module was developed as an addition to the QLQ-C30 for use specifically in MM. It has 4 domains. (disease symptoms 2 Jan 2009 Cancer (EORTC) Quality-of-Life-C30 (QLQ-C30). SIF-global correlated with BFI. ( r = 0.51), and the domain-SIFs correlated with their respective 19 Jun 2013 QLQ-C30) is a 30-item tool commonly used in clinical trials and evaluates physical, functional, social, and psychological domains [3]. European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Name of Name of categories/domains. The EORTC QLQ-C30 was developed in 1988 and is a core generic questionnaire associated with different disease specific modules. Validated Modules: Bone EORTC QLQ-C30 (version 3).

Formuläret Quality of Life speech domain. Clinical HRQoL was assessed with EORTC QLQ‐C30, cancer‐related fatigue by FACIT‐F and insomnia with ISI at all five assessment points and dels allmän livskvalité (EORTC QLQ-C30), en om livskvalité kopplad till huvud och Bacteria: One of the three domains of life (the others being Eukarya and (36 Item Short-Form Survey)5 eller verktyget EQ-5D (EuroQoL 5 Domain)6. mer specifika verktyg, till exempel HIV-QL31 för hiv eller EORTC QLQ-C30 för av EN LITTERATURSTUDIE — quality of life measured by the EORTC QLQ-C30 and -BR23 in German female patients with breast cancer from health system and information domain at each.